HPD officials work to cover shortage of certified officers

first_img By Linda Kor Holbrook Police Chief Mark Jackson informed the city council last week that his department is in the hiring process to fill a number of vacancies. Adding to the shortage of officers wasSubscribe or log in to read the rest of this content. Bottom Ad November 1, 2017 HPD officials work to cover shortage of certified officerslast_img

Trump slaps fresh sanctions on Iran says Lets make Iran great again

first_imgIran’s Foreign Ministry summoned a United Arab Emirates envoy on Saturday because the UAE allowed the drone to be launched from a US military base on its territory, the Fars news agency reported.The Iranian foreign minister, Mohammad Javad Zarif, published a map on Twitter with detailed coordinates which he said showed the drone was flying over the Islamic Republic’s territorial waters.US Secretary of State Mike Pompeo said in a statement on Saturday that the United States had “shown beyond any doubt” that the drone was in international airspace.“When the Iranian regime decides to forgo violence and meet our diplomacy with diplomacy, it knows how to reach us,” he said. “Until then, our diplomatic isolation and economic pressure campaign against the regime will intensify.”He also denied reports US forces would evacuate personnel from a military base in neighboring Iraq over what military sources had said were “potential security threats.”Flights ReroutedTensions in the region began to worsen significantly when Trump pulled out of a 2015 nuclear deal between Iran and six powers and reimposed sanctions on the country. The sanctions had been lifted under the pact in return for Tehran curbing its nuclear program.The United States and Iran’s main regional rival Saudi Arabia have also blamed Iran for attacks on two oil tankers last week in the Gulf of Oman and on four tankers off the United Arab Emirates on May 12. Both incidents happened near the strategic Strait of Hormuz, a major conduit for global oil supplies. Iran has denied any involvement.On Thursday, the Pentagon launched a long-planned cyber attack in retaliation for the oil tanker incidents, Yahoo News reported, citing former intelligence officials. The cyber strike disabled Iranian rocket launch systems, the Washington Post said on Saturday.A Department of Defense spokeswoman said it would not comment on cyberspace operations, intelligence or planning.Washington, meanwhile, accused Tehran of stepping up cyber attacks. Chris Krebs, director of the Department of Homeland Security’s cybersecurity agency, said on Twitter that officials have detected a rise in “malicious cyber activity” directed at the United States by people tied to the Iranian government.World powers have called for calm and sent in envoys for talks to try to lower the temperature of a dispute that has pushed up the price of oil.German Chancellor Angela Merkel called on Saturday for a political resolution of the crisis, adding: “That is what we are working on.”Britain’s Foreign Office said Middle East minister Andrew Murrison would visit Tehran on Sunday to raise concerns about “Iran’s regional conduct and its threat to cease complying with the nuclear deal.”Iran has threatened to breach the deal if the European signatories to the agreement fail to salvage it by shielding Tehran from US sanctions.“The Europeans will not be given more time beyond July 8 to save the deal,” Mousavi said, referring to Iran’s deadline of 60 days that Tehran announced in May.The US Federal Aviation Administration on Thursday prohibited US operators from flying in Tehran-controlled airspace over the Strait of Hormuz and Gulf of Oman. Saudi Arabian Airlines joined some other international airlines on Saturday in taking related precautions.Iran said on Saturday that its airspace was “safe and secure” for all planes to cross, Tasnim reported. US House votes to set aside impeachment resolution against Trump Separately, Iran has executed a former contract employee for the aerospace organisation of the Ministry of Defence on charges of spying for the US Central Intelligence Agency, the IRIB news agency reported on Saturday. Both Trump and Tehran have said they are not seeking a war, but Iran has warned of a “crushing” response if attacked.“Regardless of any decision they (US officials) make… we will not allow any of Iran’s borders to be violated. Iran will firmly confront any aggression or threat by America,” Foreign Ministry spokesman Abbas Mousavi told the semi-official Tasnim news agency on Saturday.A senior commander of the elite Revolutionary Guards struck a similarly defiant note, in comments quoted by the Islamic Republic News Agency (IRNA).“If the violation is repeated then our response will be repeated,” said Brigadier General Amirali Hajizadeh, head of the Guards’ aerospace division. “It’s possible that this infringement of the Americans was carried out by a general or some operators.” After Masood Azhar blacklisting, more isolation for Pakistan Military action was “always on the table,” the president said, but he added that he was open to quickly reaching a deal with Iran that he said would bolster the country’s flagging economy.“We will call it ‘Let’s make Iran great again’,” Trump said.He later wrote on Twitter from Camp David: “We are putting major additional Sanctions on Iran on Monday. I look forward to the day that Sanctions come off Iran, and they become a productive and prosperous nation again.”The Trump administration has sought to use promises of economic revival to solve other thorny foreign policy challenges, including the Israel-Palestinian peace process, with the White House outlining on Saturday a plan to create a global investment fund to lift the Palestinian and neighboring Arab state economies. trump, trump iran sanctions, iran sanctions, new iran sanctions, us iran sanctions, us iran relations, us iran news, hassan rouhani, world news, indian express news US President Donald Trump said military action on Iran was “always on the table”, but he added that he was open to quickly reaching a deal that would bolster the Iran’s flagging economy. (Source: The New York Times)US President Donald Trump said on Saturday he would impose fresh sanctions on Iran but that he wanted to make a deal to bolster its flagging economy, an apparent move to defuse tensions following the shooting down of an unmanned US drone this week by the Islamic Republic. Advertising On Thursday, an Iranian missile destroyed a US Global Hawk surveillance drone, an incident that Washington said happened in international airspace. Trump later said he had called off a military strike to retaliate because it could have killed 150 people.Tehran repeated on Saturday that the drone was shot down over its territory and said it would respond firmly to any US threat.Speaking in Washington on Saturday before heading to the US presidential retreat at Camp David, Trump indicated the government was taking a diplomatic path to put pressure on Tehran by moving to impose new sanctions. Virat Kohli won’t have a say in choosing new coach By Reuters |Dubai, Washington | Published: June 23, 2019 7:09:08 am Karnataka trust vote today: Speaker’s call on resignations, says SC, but gives rebel MLAs a shield Related News Best Of Express Advertising More Explained Taking stock of monsoon rain Trump says ‘will take a look’ at accusations over Google, China Unbowed, Trump intensifies attacks on four Democratic congresswomen 2 Comment(s) Advertisinglast_img read more

Trump Xi talks Modis selfie with Morrison — Key points from Day

first_img Advertising Advertising Advertising After Masood Azhar blacklisting, more isolation for Pakistan Karnataka trust vote today: Speaker’s call on resignations, says SC, but gives rebel MLAs a shield Modi’s selfie with Australian PM Scott MorissonAustralian Prime Minister Scott Morrison and Modi posed a selfie on the second day of the summit sharing some light moments with each other amid hectic schedules.Morrison clicked a selfie with Modi and posted it on Twitter with a captain “Kithana acha he Modi!” (How good is Modi). To which, PM Modi had a very unique response for his mate, signifying his adeptness of acing the bilateral ties and social media presence in one go.PM Modi met Turkish President, holds talks on counter-terrorismTurkish President Recep Tayyip Erdogan and Modi held talks on a host of key issues including trade and investment, defence and counter-terrorism at the G20 summit today. The Turkish leader, during a two-day visit to India in July, 2018, assured India of his country’s full support in the fight against terrorism.PM Modi met Brazil president Jair Bolsonaro Deepening the close and multifaceted strategic partnership, Modi and his Brazilian counterpart Jair Bolsonaro held wide-ranging discussions on the bilateral relationship, including cooperation in trade and investment, agriculture and biofuels in the context of climate change. Taking stock of monsoon rain Virat Kohli won’t have a say in choosing new coach Prime Minister Narendra Modi, center, attends the session 3 on women’s workforce participation, future of work, and aging societies at the G-20 Summit in Osaka. (AP photo) On day two of the G-20 summit in Japan’s Osaka, Prime Minister Narendra Modi held a series of bilateral meetings with world leaders, individually and in groups. He met with presidents of Indonesia, Brazil, and Turkey. No setbacks in S-400 deal with Russia: Tayyip Erdogan Turkish President Tayyip Erdogan said that there were no setbacks in Russian S-400 missile defence systems deal, adding that “eyes are on the delivery process”, expected in the first half of July. Erdogan, speaking before talks with Russian President Vladimir Putin on the sidelines of a G20 summit in Japan, also said it was important to finish the first reactor in the Akkuyu nuclear power plant by 2023. Erdogan is also due to meet US President Donald Trump in Osaka.IMF Lagarde urges G20 members to reduce tariffs, trade barriersInternational Monetary Fund Managing Director Christine Lagarde on Saturday urged G20 policymakers to reduce tariffs and other obstacles to trade, warning that the global economy had hit a “rough patch” due to the trade conflict.“While the resumption of trade talks between the United States and China is welcome, tariffs already implemented are holding back the global economy, and unresolved issues carry a great deal of uncertainty about the future,” Lagarde said in a statement issued upon conclusion of the Group of 20 summit in Osaka, western Japan. Best Of Express g20 summit, g20, donald trump, xi jinping, us china trade tension, us china tariff war, donald trump meets xi jinping, US news, China news US President Donald Trump meets with China’s President Xi Jinping at the start of their bilateral meeting at the G20 leaders summit in Osaka on Saturday. (Reuters)China, US agree to restart trade talks After holding bilateral talks with Xi at the G-20 Summit in Osaka Saturday, Trump said that the US will not levy new tariffs on Chinese exports, news agency Reuters reported.Ahead of the talks, Trump had said he was open to a potentially “historic” trade deal with China. “I actually think that we were very close and … that something happened where it slipped a little bit, and now we’re getting a little bit closer,” Trump told Xi as the cameras rolled at the start of the closely-watched talks.India refuses to sign declaration on free flow of data across bordersIn a sign of resistance against developed countries led by the US and Japan, which are pushing for free flow of data across borders, India Friday refused to become a signatory to the Osaka declaration on digital economy that was signed by 24 countries and groupings.While a majority of G-20 countries signed off on the launch of “Osaka track”, an overarching framework promoting cross-border data flow with enhanced protections launched by Japan Prime Minister Shinzo Abe, India was joined by South Africa and Indonesia in keeping away. By Express Web Desk |New Delhi | Published: June 29, 2019 12:10:25 pm In the meanwhile, US President Donald Trump held trade talks with his Chinese counterpart Xi Jinping. Here’s everything that has happened on the concluding day of G-20 Summit in Japan:India, Indonesia set $50-billion trade target by 2025India and Indonesia set an ambitious $50 billion target for bilateral trade over the next six years as Modi and President Joko Widodo discussed ways to deepen cooperation in a number of key areas including economy, defence, and maritime security.Trade between the two countries in 2016 was $12.9 billion. It rose 28.7 per cent to $18.13 billion in 2017 with Indonesia’s exports to India reaching $14.08 billion and its imports from India standing at $4.05 billion, according to Indonesia’s Central Statistics Agency. More Explained Related News G20 Summit: US-China trade talks, climate change dominate final session Modi, Erdogan talk S-400 air defence deal, US sanctions G-20 leaders showcase support for women’s empowerment Ivanka Trump, adviser to President Donald Trump said, the world economy would get a boost of up to $28 trillion by 2025 if women were on an equal economic footing. She was speaking at a special session on the issue at the G-20 summit in Osaka that included her father. She described improving the status of women as “smart economic and defense policy.” G20 summit: India pitches strongly for fight against fugitive economic offenders Post Comment(s)last_img read more

US will not blacklist Irans foreign minister for now

first_imgThe State Department did not immediately respond to a request for comment on the decision.The department’s spokeswoman Morgan Ortagus said on Thursday Washington wants a diplomatic resolution and repeated Trump’s comment that he is willing to meet Iran “without preconditions.”“We seek a diplomatic solution,” she told reporters. “We have asked our allies to ask Iran to deescalate the situation, not to harass American allies or interests, not to terrorize the region.”Mnuchin did not say what sanctions would hit Zarif. On the day he spoke, he was briefing reporters on US sanctions that aimed to block Iran’s supreme leader, Ali Khamenei, from access to the US financial system or assets under US jurisdiction.On July 4, the New York Times quoted Zarif as saying in an email that he did not own any property or have any bank accounts outside Iran. “So I have no personal problem with possible sanctions,” he said.‘WE SEEK A DIPLOMATIC SOLUTION’Trump has said he is open to negotiating with Iran. However, former US officials said they see no signs his administration is interested in talks on terms other than Iran’s capitulation to US demands.As laid out by Pompeo last year, these include Tehran ending uranium enrichment, a process that can produce fissile material for atomic bombs; giving U.N. nuclear inspectors total access to sites throughout the country; releasing US citizens held in Iran and withdrawing Iranian forces from Syria.The former officials, who spoke on condition of anonymity, said a decision not to sanction Zarif could be a hint Washington wants to preserve the option of diplomacy even if it appears unlikely for now.Trump administration officials seem particularly hostile to Zarif, possibly because of his use of Twitter to taunt them as a “B-team” of second-raters who “despise diplomacy, and thirst for war.”If Washington wanted to get into a negotiation with Tehran, it could send other conciliatory signals.One would be to allow a quiet stabilization of Iran’s oil exports, which stood at 2.5 million barrels per day (bpd) before Trump abandoned the deal and have since fallen to about 300,000 bpd since Trump’s May decision to try to drive them to zero.Rather than renew sanctions waivers to allow nations such as China and India to keep buying Iran’s oil, Washington could just turn a blind eye to continued purchases, the former US officials said.That seems unlikely after British Royal Marines seized the Grace 1 supertanker off the coast of Gibraltar last week amid accusations that it had broken sanctions by carrying Iranian oil to Syria. Related News Karnataka trust vote today: Speaker’s call on resignations, says SC, but gives rebel MLAs a shield Iran, Iran US, US Iran, Mohammad Javad Zarif, Zarif Iran, Iran foreign minister, Iran foreign minister blacklist, US Iran, Iran US nuclear treaty, US Iran nuclear treats, Indian Express, World news FILE – In this Nov. 29, 2015, file photo, Iranian Foreign Minister Mohammad Javad Zarif listens to a question during a news conference in Tehran, Iran. (AP/File)“Cooler heads prevailed. We … saw it as not necessarily helpful,” said one source familiar with the matter who spoke on condition of anonymity, saying US Secretary of State Mike Pompeo had opposed designating Zarif “for the time being.”Read |  The Iran crisis: How we got there and what’s nextIn a sign of how close Washington came to taking action, the US Treasury internally circulated a draft press release announcing sanctions on the Iranian foreign minister.Zarif is expected to attend a ministerial meeting at the United Nations next week on sustainable development goals, which aim to tackle issues including conflict, hunger, gender equality and climate change by 2030.Explained | Iran’s nuclear program as 2015 deal unravels Best Of Express Another possible hint would be for the Trump administration to renew waivers – which expire in early August – that allow China, Russia and European nations to pursue nuclear nonproliferation projects with Iran. Iran, Iran US, US Iran, Mohammad Javad Zarif, Zarif Iran, Iran foreign minister, Iran foreign minister blacklist, US Iran, Iran US nuclear treaty, US Iran nuclear treats, Indian Express, World news FILE PHOTO: Iran’s Foreign Minister Mohammad Javad Zarif sits for an interview with Reuters in New York, New York, U.S. April 24, 2019. (Reuters)The United States has decided not to impose sanctions on Iranian Foreign Minister Mohammad Javad Zarif for now, two sources familiar with the matter said on Thursday, in a sign Washington may be holding a door open for diplomacy. To do so, the United States would have to grant him a visa, another sign Washington is holding off on sanctions for now.ZARIF SAYS HE HAS NO US ASSETSRelations have deteriorated since US President Donald Trump last year unilaterally withdrew from Iran’s 2015 nuclear deal with major powers, and his early May decision to use US sanctions to try to eliminate Iran’s oil exports entirely.Trump’s move to cut off Iran’s oil sales led Tehran to start violating parts of the nuclear pact, which was designed to limit its ability to develop weapons in return for relief from economic sanctions that had crippled its economy.Also read | Delhi to Tehran via USAsked why Zarif had yet to be sanctioned, a Treasury spokesman referred to a comment on Tuesday by a senior Trump administration official who told reporters: “We’re obviously exploring our various avenues for additional sanctions against Tehran. Obviously, Foreign Minister Zarif is a figure of key interest and we’ll update you … as we have more information.” UK says seized Iranian oil tanker could be released With Iran deal teetering on brink, Europeans assess next steps Hassan Rouhani says Iran ready to talk to US if sanctions lifted Advertising More Explained Advertising After Masood Azhar blacklisting, more isolation for Pakistan Treasury Secretary Steven Mnuchin on June 24 had said Zarif would be blacklisted that week, an unusual public stance because the United States typically does not preview such decisions to keep its targets from moving assets out of US jurisdiction.Blacklisting Iran’s chief negotiator would also be unusual because it could impede any US effort to use diplomacy to resolve its disagreements with Tehran over Iran’s nuclear program, regional activities and missile testing.The sources did not give specific reasons for the decision, which came after two months in which US-Iranian tensions have soared because of attacks on tankers in the Gulf that the United States blames on Iran, despite its denials, and Iran’s downing of a US drone that prompted preparations for a US retaliatory air strike that was called off minutes before it was due to hit. 1 Comment(s) By Reuters |Washington | Published: July 12, 2019 7:54:24 am Taking stock of monsoon rain Cabinet asks finance panel to consider securing funds for defence Advertisinglast_img read more

Contraception deserts likely to widen under new Trump administration policy

first_imgWhen Nikia Jackson needed to be screened for a sexually transmitted disease, she wanted a clinic that was reputable, quick and inexpensive.After searching online, Jackson, 23, ended up at the Obria Medical Clinics’ sparkling new facility in an office park in suburban Atlanta. She was unaware that the clinic does not offer condoms or other kinds of birth control beyond so-called natural family planning methods.Religious conservatives say these types of clinics are the future of women’s sexual health care in the United States.”A woman needs choice, but you can’t have a choice if the only clinic that a woman can go to is Planned Parenthood,” said Kathleen Bravo, chief executive of the Obria Group and a devout Catholic.Young women, she said, “don’t want to live every day having to take a carcinogen,” referring to hormonal contraception.For decades, contraception drew widespread bipartisan support, but since the passage of the Affordable Care Act in 2010, religious conservatives trained their ire on the law’s contraception mandates, and the politics of abortion and birth control converged.Bravo is positioning her company to become a nationwide alternative to Planned Parenthood and aims for it to qualify for millions of dollars in federal family planning funds next year. With 38 clinics and 22 more slated to open, Obria offers tests for pregnancy, STIs, HIV and cervical cancer and prenatal care.But patients seeking to prevent pregnancy can receive only fertility planning methods that require women to track their periods and refrain from sex when most fertile. When followed exactly, the method is 76 percent effective, according to the Centers for Disease Control and Prevention.That vision has found favor with the Trump administration, which has proposed sweeping changes to a $280 million federal program called Title X, the only source of federal funds for birth control for low-income women who lack health insurance.For more than four decades, thousands of women’s health clinics, including Planned Parenthood affiliates, that received these federal funds have been required to offer a full range of medically effective contraception, including condoms, birth control pills, intrauterine devices and implants. (The clinics cannot use federal funds to pay for abortion, and many Title X clinics do not offer the procedure.)But with Title X now under the direction of Dr. Diane Foley, the former chief executive of Life Network, a Christian organization that operates anti-abortion pregnancy centers, the Trump administration is widely expected to adopt rules in the coming months that promote and direct federal dollars to clinics like Obria that do not offer condoms, hormonal contraception, intrauterine devices or abortion.Called the “Protect Life Rule,” the new restrictions are aimed at narrowing women’s access to clinics that discuss or refer patients to abortion providers. The Trump administration has worked quickly to shape women’s reproductive health care, rolling back an Obama-era rule that required employers to cover contraception in their health insurance plans and nominating to the Supreme Court Judge Brett Kavanaugh, who referred to common forms of contraception as “abortion-inducing drugs” during his confirmation hearing.With Vice President Mike Pence, an evangelical Christian, as a powerful ally and anti-abortion and abstinence advocates, including Foley, appointed by the Trump administration overseeing key federal health programs, religious conservatives are seizing this moment to shape women’s sexual health care.In 2011, anti-abortion state lawmakers sought to shutter Planned Parenthood clinics and slashed state funding for family planning by 66 percent. As a result, more than 80 family planning clinics closed, and women across Texas suddenly found their birth control needs caught up amid the fight against abortion.The impact was swift and widespread: Researchers found the number of women on the most effective forms of birth control – IUDs, implants and injections – plunged by a third, and births by poor women on Medicaid increased 27 percent from 2011 to 2014.In the aftermath, family planning clinics in Texas became almost entirely dependent on Title X federal funds. Now many administrators here and around the country are bracing for the Trump administration’s new rules.Kathryn Hearn, community services director at Access Esperanza in McAllen, Texas, said clinics that offer the full range of FDA-approved birth control could be replaced by those like Obria.Related StoriesContraceptive jewelry may be new approach to family planning for womenUnisex, hormone-free contraceptive pill on the horizonNew protein target for deadly ovarian cancer”Today a woman can come into a Title X clinic, any clinic in the United States, in Texas, and be offered a wide range of contraceptive methods,” she said. “With these proposed rules, she could only be offered abstinence. Well, she says, I’m married. Or I’m in a relationship. That does not work for me. I need real contraceptive care.”Ofelia Alonso, a 22-year-old community organizer, said that because of deceptive tactics and lack of comprehensive sex education, young women in Texas already find it difficult to discern between medical clinics and crisis pregnancy centers, offices where women are counseled against abortion.”It’s like abstinence only, and then, crisis pregnancy centers, anti-abortion propaganda, defunding our family clinics. So what is left for us?” Alonso said. “We’re going to have these weird centers where you can’t get anything?”But women seeking contraception have to go somewhere, and one alternative, she said, is to cross the nearby border into Mexico to buy birth control over the counter.”It shouldn’t have to be that way,” she said. “We shouldn’t have to travel to another country to get what we need.”Some uninsured patients in Texas do find alternative ways to get birth control.Claire Hammons runs an historic hotel in Llano, a small city an hour and half west of Austin with no full-service women’s health clinic.The vast geography combined with widespread clinic closures means that some 10 million Texans live at least half an hour from a clinic, a common standard used to determine health care shortages. It’s a phenomenon some call “contraception deserts.”Hammons lives in one of these contraception deserts and when she could no longer afford health insurance, she turned to the internet for help. Now, she gets her birth control delivered every three months to her mailbox from a San Francisco-based company called Nurx. She pays about $15 a month and can message Dr. Jessica Rubino, a Nurx physician in Austin. Rubino can review her patients’ medical histories and renew their prescriptions without additional cost.Rubino said she sees what happens to women who live in contraception deserts.”I’m also an abortion provider, and I do that outside of Nurx at another facility,” she said. “I had one [patient] last week who drove five hours to see me. And the entire reason that she came to see me for the abortion is because she didn’t have any access to contraception.”That lack of access worries Kami Geoffray, CEO of the Women’s Health and Family Planning Association of Texas, the nonprofit group that has coordinated the state’s application for Title X funds.If the Trump administration’s overhaul of Title X succeeds, Geoffray said, it will undermine the goal of the program that the federal government has operated since the 1970s.”We know that every dollar we spend on Title X saves $7 across other government programs, including Medicaid,” said Geoffray. “We avert Medicaid births very frequently by [getting contraception for] clients and preventing unplanned pregnancies.”But back in suburban Atlanta at the Obria Medical Clinic, Bravo has declared it’s time for companies like hers to put a bigger mark on reproductive health care. The company is launching a $240 million capital campaign to open more clinics.”Obria is a comprehensive primary care clinic for women that is an alternative model to Planned Parenthood,” said Bravo. “We put huge amounts of money into marketing our clinics, like all medical clinics do, to make sure that women know that we’re here in their city.”KHN’s coverage of women’s health care issues is supported in part by The David and Lucile Packard Foundation. Reviewed by Alina Shrourou, B.Sc. (Editor)Sep 28 2018 This article was reprinted from khn.org with permission from the Henry J. Kaiser Family Foundation. Kaiser Health News, an editorially independent news service, is a program of the Kaiser Family Foundation, a nonpartisan health care policy research organization unaffiliated with Kaiser Permanente.last_img read more

Mannose nutritional supplement could slow some cancers

first_imgBy Dr. Ananya Mandal, MDNov 21 2018Mannose is a sugary nutritional supplement that has shown promise in slowing down the growth of certain cancers in laboratory mice. The results of the five year-long study from Glasgow were published in the latest issue of the journal Nature.The team of researchers gave mannose to mice with simulated pancreatic, lung or skin cancers. There were no side effects while the cancer growth slowed significantly. Mannose is also found naturally in cranberries and other fruits, the authors explain. Researchers warn however that it is too early to know the direct connection and people should not start supplementing with mannose because it carries risk of side effects. The team of researchers gave mannose supplements to mice with the cancers that were also being treated with anticancer drugs such as cisplatin and doxorubicin. On administration of mannose the chemotherapy effects were enhanced, they add. The tumours shrunk in size and the mice lived longer. The team then exposed other cancer cells from bone cancer (osteosarcoma), leukaemia, bowel cancer and ovarian cancer and found that some of the cells responded while others did not respond to mannose in the laboratory set up. They noted that cells that contained high levels of the enzyme phosphomannose isomerase (PMI) were less likely to respond to mannose.Related StoriesTrends in colonoscopy rates not aligned with increase in early onset colorectal cancerUsing machine learning algorithm to accurately diagnose breast cancerStudy: Nearly a quarter of low-risk thyroid cancer patients receive more treatment than necessaryAccording to lead author Prof Kevin Ryan, from the Cancer Research UK Beatson Institute, the principle behind mannose and its benefits in tumours was the fact that it could block the uptake of glucose by the tumour and thus effectively starve it and slow its growth. Mannose did not affect the surrounding healthy cells which led to the side-effect free profile. He said, “This is early research, but it is hoped that finding this perfect balance means that, in the future, mannose could be given to cancer patients to enhance chemotherapy without damaging their overall health.”The team hopes that they can start testing the supplement on human cancer patients soon and would know if it actually worked in humans as well. The team needs to understand why some cancers respond to mannose while others do not, Prof Ryan said.Martin Ledwick, Cancer Research UK’s head nurse warned that these results have not yet been extrapolated in humans and people with cancer should not start supplementing their diet with mannose. Dr Helen Rippon, chief executive of Worldwide Cancer Research too lauded this study saying, “This is a brand-new discovery and only the first step in working out whether mannose might help treat cancer.”This study received support from the Cancer Research UK and Worldwide Cancer Research.Source: https://www.nature.com/articles/s41586-018-0729-3 Cranberries, a natural source of mannose. Image Credit: Tim UR / Shutterstocklast_img read more

The Vegan Society EU ban on meaty names for veggie food products

first_imgThe Vegan Society has highlighted the proposed measures will not only impact vegans, but also public authorities that currently serve vegan food, such as government departments, health providers, education establishments, police forces and prisons.It has legally challenged the plans in a formal letter to EU officials, signed by its CEO and prepared by a legal expert, on the grounds of breaching fundamental human rights of vegans that are set out by the Union.The letter states the proposed measures contravene the EU consumers’ right to be informed adequately as to how goods can be used and denies the vegan community the benefits offered by EU law on clear labeling.If the proposals are voted into effect next month, vegan and veggie burgers could become ‘discs’, and sausages ‘tubes’ among other products.George Gill, CEO at The Vegan Society who signed the letter, said: Dr Rowley quotes in the letter the European food labeling laws that state “food information should … enable consumers to identify and make appropriate use of food” and argues the use of ‘meaty’ names informs the consumer how the plant-based products can be cooked and used. The 14-page letter includes an appendix with over 100 examples of plant-based food descriptors being used in the public and private sectors, suggesting many institutions would be affected.Public authorities are obliged to provide plant-based food to vegans in their care as veganism is a protected philosophical belief under the Equality Act 2010.Excessive amounts of time and money would have to be unnecessarily spent on revising menus in public sector institutions if the proposals are accepted.Dr Jeanette Rowley, Vegan Rights Advocate at The Vegan Society, said: This proposed measure is not aligned with EU policy on respect for diversity.It is not in the public interest and, if implemented, would have a disproportional impact across society by affecting the normal daily functioning of all public and private entities that provide food.This EU measure threatens to cause widespread administrative chaos, confusion and time wasting trying to understand how to plan a meal that includes a veggie disc or a veggie tube!The widespread impact of this unreasonable and costly proposal should not be underestimated.” Apr 23 2019A vegan charity has warned the proposals to ban the use of traditional names like ‘burger’ and ‘sausage’ for vegan and veggie food products will result in “excessive administrative burdens” to all public entities. As consumers are increasingly moving away from eating animals, the demand for vegan products is growing. There’s no denying that meat, dairy and egg industries are feeling threatened by this and desperately trying to restrict the marketing of vegan products.These proposals have little to do with consumer protection and instead are motivated by economic concerns of the meat industry. We are calling on EU officials to reject these irrational measures for vegan meat alternatives to be banned from using the qualified conventional terms everyone has been using for decades.” Related StoriesAn active brain and body associated with reduced risk of dementiaSmarter, more educated people get a cognitive ‘head start’, but aren’t protected from Alzheimer’sVegans are often deficient in these four nutrientsThe Vegan Society dismissed what it sees as unlawful proposals, calling them “an attempt to bolster a depressed agricultural economy” and warned they would “create confusion across the EU” if put in place.It argued the proposed measures do not achieve the required threshold for implementation as the EU rules recognize that “any limitation of fundamental rights must respect the principle of proportionality and meet objectives of general interest”.The rights and equality provisions available to the vegan community have not been included in the assessment of the validity of the proposed measure, which has not, according to the charity, taken into account all relevant stakeholders in the EU community.Alternative vocabulary put forward such as ‘vegetable disc’ does not constitute clear food labeling under EU consumer law because such terms do not describe or facilitate ease of interpretation, nor make it easy to perceive the food item in question.The EU has 21 days to respond to the letter, after which the matter will be escalated by The Vegan Society.Source: https://www.vegansociety.com/whats-new/news/eu-ban-%E2%80%98meaty%E2%80%99-names-would-financially-impact-public-sector-not-just-veganslast_img read more

Intermittent fasting may protect against type 2 diabetes

first_imgUnder certain genetic conditions, the accumulation of fat in the pancreas may play a decisive role in the development of type 2 diabetes.”Professor Tim J. Schulz, head of the Department of Adipocyte Development and Nutrition Reviewed by Kate Anderton, B.Sc. (Editor)Jul 2 2019Intermittent fasting is known to improve sensitivity to the blood glucose-lowering hormone insulin and to protect against fatty liver. DZD scientists from DIfE have now discovered that mice on an intermittent fasting regimen also exhibited lower pancreatic fat. In their current study published in the journal Metabolism, the researchers showed the mechanism by which pancreatic fat could contribute to the development of type 2 diabetes.Fatty liver has been thoroughly investigated as a known and frequently occurring disease. However, little is known about excess weight-induced fat accumulation in the pancreas and its effects on the onset of type 2 diabetes. The research team led by Professor Annette Schürmann and Professor Tim J. Schulz of the German Institute of Human Nutrition (DIfE) has now found that overweight mice prone to diabetes have a high accumulation of fat cells in the pancreas. Mice resistant to diabetes due to their genetic make-up despite excess weight had hardly any fat in the pancreas, but instead had fat deposits in the liver. “Fat accumulations outside the fat tissue, e.g. in the liver, muscles or even bones, have a negative effect on these organs and the entire body. What impact fat cells have within the pancreas has not been clear until now,” said Schürmann, head of the Department of Experimental Diabetology at DIfE and speaker of the German Center for Diabetes Research (DZD).Intermittent fasting reduces pancreatic fatThe team of scientists divided the overweight animals, which were prone to diabetes, into two groups: The first group was allowed to eat ad libitum – as much as they wanted whenever they wanted. The second group underwent an intermittent fasting regimen: one day the rodents received unlimited chow and the next day they were not fed at all. After five weeks, the researchers observed differences in the pancreas of the mice: Fat cells accumulated in group one. The animals in group two, on the other hand, had hardly any fat deposits in the pancreas.Pancreatic adipocytes mediate hypersecretion of insulin In order to find out how fat cells might impair the function of the pancreas, researchers led by Schürmann and Schulz isolated adipocyte precursor cells from the pancreas of mice for the first time and allowed them to differentiate into mature fat cells. If the mature fat cells were subsequently cultivated together with the Langerhans islets of the pancreas, the beta cells of the “islets” increasingly secreted insulin. “We suspect that the increased secretion of insulin causes the Langerhans islets of diabetes-prone animals to deplete more quickly and, after some time, to cease functioning completely. In this way, fat accumulation in the pancreas could contribute to the development of type 2 diabetes,” said Schürmann.Significance of pancreatic fat for diabetes preventionCurrent data suggest that not only liver fat should be reduced to prevent type 2 diabetes. Related StoriesUTHealth researchers investigate how to reduce stress-driven alcohol useNew biomaterial could encapsulate and protect implanted insulin-producing cellsSome people treated for type 1 diabetes may have monogenic diabetes, study findsIntermittent fasting could be a promising therapeutic approach in the future. The advantages: it is non-invasive, easy to integrate into everyday life and does not require drugs.Intermittent fastingIntermittent fasting means not eating during certain time slots. However, water, unsweetened tea and black coffee are allowed around the clock. Depending on the method, the fasting lasts between 16 and 24 hours or, alternatively, a maximum of 500 to 600 calories are consumed on two days within a week. The best known form of intermittent fasting is the 16:8 method which involves eating only during an eight-hour window during the day and fasting for the remaining 16 hours. One meal – usually breakfast – is omitted.Islets of LangerhansThe islets of Langerhans – also referred to as islet cells or Langerhans islets – are islet-like accumulations of hormone-producing cells in the pancreas. A healthy adult has about one million Langerhans islets. Each “islet” has a diameter of 0.2-0.5 millimeters. The beta cells produce the blood glucose-lowering hormone insulin and make up about 65 to 80 percent of the islet cells. When blood glucose levels are elevated, these secrete insulin into the bloodstream so that the levels are normalized again. Source:Deutsches Zentrum fuer Diabetesforschung DZDJournal reference:Schulz, T.J. et al. (2019) Pancreatic adipocytes mediate hypersecretion of insulin in diabetes-susceptible mice. Metabolism. doi.org/10.1016/j.metabol.2019.05.005.last_img read more

Malaysia OKs new search by private company for missing plane

Malaysia’s government said Saturday that it has approved a new attempt by a private company to find the wreckage of Malaysia Airlines Flight 370, nearly four years after its disappearance sparked one of aviation’s biggest mysteries. Citation: Malaysia OKs new search by private company for missing plane (2018, January 7) retrieved 18 July 2019 from https://phys.org/news/2018-01-malaysia-oks-private-company-plane.html Scientists potentially narrow MH370 search area to 3 spots Explore further This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. More information: oceaninfinity.com/ The Houston, Texas-based company Ocean Infinity dispatched a search vessel this past week to look in the southern Indian Ocean for debris from the plane, which disappeared March 8, 2014, on a flight from Kuala Lumpur to Beijing with 227 passengers and 12 crew members.The governments of Malaysia, China and Australia called off the nearly three-year official search last January. The Australian Transport Safety Bureau’s final report on the search conceded that authorities were no closer to knowing the reasons for the Boeing 777’s disappearance, or its exact location.”The basis of the offer from Ocean Infinity is based on ‘no cure, no fee,'” Malaysian Transport Minister Liow Tiong Lai said Saturday, meaning that payment will be made only if the company finds the wreckage.”That means they are willing to search the area of 25,000 square kilometers (9,653 square miles) pointed out by the expert group near the Australian waters,” he said.However, he said, “I don’t want to give too much hope … to the (next of kin).” He said his government was committed to continuing with the search.He did not offer other details.Ocean Infinity said in a statement that the search vessel Seabed Constructor, which left the South African port of Durban on Tuesday, was taking advantage of favorable weather to move toward “the vicinity of the possible search zone.”In the initial search for the plane, a 52-day surface search covered an area of several million square kilometers (square miles) in the Indian Ocean west of Australia, before an underwater search mapped 710,000 square kilometers (274,000 square miles) of seabed at depths of up to 6,000 meters (20,000 feet). They were the largest aviation searches of their kind in history, according to the Australian Transport Safety Bureau (ATSB).Despite other methods such as studying satellite imagery and investigating ocean drifts after debris from the plane washed ashore on islands in the eastern Indian Ocean and the east coast of Africa, the 1,046-day search was called off on Jan. 17, 2017.However, the ATSB’s report said the understanding of where the plane may be is “better now than it has ever been,” partly as a result of studying debris that washed ashore in 2015 and 2016 that showed the plane was “not configured for a ditching at the end-of-flight,” meaning it had run out of fuel.The search team also looked back at satellite imagery that showed objects in the ocean that may have been MH370 debris. The report said this analysis complemented work detailed in a 2016 review and identified an area of less than 25,000 square kilometers (9,650 square miles)—roughly the size of the U.S. state of Vermont—that “has the highest likelihood of containing MH370.”The search was extremely difficult because no transmissions were received from the aircraft after its first 38 minutes of flight. Systems designed to automatically transmit the flight’s position failed to work after this point, the report said. In this March 6, 2016, file photo, well wishes are written on a wall of hope during a remembrance event for the ill fated Malaysia Airlines Flight 370 in Kuala Lumpur, Malaysia. The Malaysian government has approved a new attempt to find the wreckage of Malaysia Airlines Flight 370 in the Indian Ocean. (AP Photo/Joshua Paul, File) © 2018 The Associated Press. All rights reserved. read more

The algorithms of our future thinking machines

“To be able to establish a research environment with such talented colleagues at KTH is great fun,” says Thomas Schön, Professor of Automatic Control at Uppsala University Provided by Uppsala University It has been almost a year since IT researchers at Uppsala University and KTH received 24 million kronor from the Swedish Research Council for the formation of the research environment “NewLEADS”. However, preparations for the project “New approaches for model-based learning of dynamical systems” were initiated already in January 2016. Collaboration between the research groups goes even further back, says Thomas Schön, Professor of Automatic Control at Uppsala University.”We know each other well from before and have co-written research papers. To be able to establish a research environment with such talented colleagues at KTH is great fun. Together we can do amazing things that would be impossible for only one individual to pull off.”When it comes to dividing the work between the two universities, it mainly comes down to each research group’s expertise.”Uppsala’s focus in this project is to build mathematical models of dynamic systems that can identify and deal with uncertainty. No matter how talented we are, models still never align perfectly with real life—we can never cover all possible aspects. However, we can construct mathematical manoeuvres that help machines to make independent and reliable decisions,” says Thomas Schön.Safer decision-making systemThe challenge of constructing algorithms for dynamic systems is in the nature of those systems: they are in constant change. Traffic cameras, radar, and inertial sensors are some of the devices delivering the information the algorithm requires. Now another extremely dynamic system is becoming more central to Thomas Schön’s and his colleagues’ projects: the human body.”We are increasing our work in the medical field and looking in particular at automated diagnosis as a tool for physicians. Today, Swedish x-rays are sent for examination by physicians in reverse time zones such as Australia. They then e-mail their reports to their colleagues in Sweden who can study them when getting in to the hospital in the morning. I believe that kind of review will to some extent be automated even if significant challenges still remain,” says Thomas Schön. This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. Behind every self-driving car, self-learning robot and smart building hides a variety of advanced algorithms that control learning and decision making. Some of the mathematical models that make up the backbone of automated systems are currently under construction by researchers from Uppsala University and KTH. Citation: The algorithms of our future thinking machines (2018, January 22) retrieved 18 July 2019 from https://phys.org/news/2018-01-algorithms-future-machines.html Researcher seeks to tame ‘ghost’ of uncertainty in complex dynamic systems Explore further The uncertainty inherent in the mathematical models are no different from the ubiquitous uncertainty in today’s diagnoses, he says. Physicians cannot possibly assimilate all new medical information. There, automated diagnosis constitutes support and contributes to new questions. In addition, a solution based on machine learning is able to quantify the uncertainty in the prediction, which according to Thomas Schön also presents the physician with important information before making the final decision.”All the data coming in results in a huge bank of knowledge for everybody to use. This is the great opportunity and the great challenge.”Breadth of qualificationsAccording to Thomas Schön, NewLEADS focuses mainly on basic research. At the same time, they maintain exchanges with projects of a more applied nature. Uppsala’s research group also includes Fredrik Lindsten, Peter Stoica and Dave Zachariah with qualifications in automatic control, signal processing and machine learning.The KTH researchers have a similar background but with a slightly different profile. One focus is to design experiments that extract as much information as possible from a particular system that is to be modelled, explains Håkan Hjalmarsson, Professor of Automatic Control at KTH. His group includes Cristian Rojas as well as Bo Wahlberg, initiator of NewLEADS. In addition, there are some ten doctoral students and post-docs involved in NewLEADS at both universities. Several Ph.D. courses are in the works.There are very good conditions for the new research environment, according to Håkan Hjalmarsson.”I hope of course that KTH and UU will be able to build a good theoretical base that is easy to implement in various applications of dynamic systems such as smart climate control of buildings and self-driving vehicles, and that we get to see them put to good use,” he says, and adds:”In six years, we probably won’t have achieved our every goal, but we stand a good chance of having come a long way. We are a fantastic team.” read more

Using drones to simplify film animation

first_imgActors’ movements can be easily recorded using commercial drones, which greatly reduces the technical effort required for animated film. Credit: ETH Zurich / Tobias Nägeli Citation: Using drones to simplify film animation (2018, December 5) retrieved 17 July 2019 from https://phys.org/news/2018-12-drones-animation.html “What makes our system so unique is that it can also reliably capture sudden and fast movements,” explains Nägeli. “Of course, this kind of demo system is not good enough to meet the requirements of the film industry yet. But it does offer a promising approach.” As the young researcher explains, the system could also be extended with additional drones to capture movement in even greater detail. It is also conceivable that the current approach with light markers could be replaced by automatic image analysis, thus reducing the technical complexity of film production even further.Sport motion analysis by drone?The team conducted various tests to show how the system can be used to track human movement over longer distances – something that makes the approach interesting for sport motion analysis. “Until now, it has been impossible to perform a comprehensive motion analysis on runners, for example, because it is much too complicated,” explains Nägeli. “With our system, it’s very easy now to examine how a runner’s kinetics changes over a period of time.”For the time being, this is still just a vision. Now, the challenge is to continue developing the system for practical applications. Together with two colleagues, Nägeli plans to tackle this task at the new start-up company Tinamu Labs. And who knows – maybe he and his drones will soon land in Hollywood. Drones are going to change the film industry in a major way. Tobias Nägeli, for one, is sure of that. The computer scientist, who recently finished his doctoral thesis with Otmar Hilliges, a professor of computer science and head of the Advanced Interactive Technologies Lab, was able to show about a year ago that spectacular, highly technical film scenes could be shot in a much easier way by using these mini aircraft. In a further project, which he presented at a conference in Tokyo in early December, he demonstrated that drones also have great potential for animated film.Drones to replace dozens of cameras”It’s a very time-consuming task to make figures look realistic in an animated film,” explains Nägeli. “For the figures to appear natural, the first step is to film an actor performing the movements. The second step is then to build the animated figure around this.” In order to reconstruct the actor’s movements for the 3-D animation, they must first be recorded with at least two cameras simultaneously. Sequences of motion that cover a great deal of space in particular create an enormous amount of technical work, so two well-positioned cameras should be able to cover the entire scene. This requires either installing numerous cameras in different places, of which only a few can be used at the same time, or other tricky installations.This complicated technique may soon be rendered obsolete. Nägeli and his colleagues at ETH Zurich and Delft University of Technology have developed a system that, in its simplest configuration, consists of two commercially available drones and a laptop. The drones follow the actor’s every move and automatically adjust their position so that the target can always be shot from two angles. This reduces the amount camera work required, since the cameras only have to be in the spots where they are actually needed. Impressively, the system anticipates the actor’s movements in real-time and then calculates where the drones need to fly in order to keep the actor in the frame. This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. Explore furthercenter_img The team conducted various tests to show how the system can be used to track human movement over longer distances. Credit: ETH Zurich / Tobias Nägeli To minimise the volume of data generated, infrared diode markers are fixed to the actor’s joints. The drones, which are equipped with a true light filter, record only the light from the markers, greatly simplifying data processing. The system only sees a few points, from which it then determines the body’s position and directional movement. Provided by ETH Zurich Spectacular images thanks to an efficient algorithm Producing realistic animated film figures is a highly complex technical endeavour. ETH researchers have now shown how drones can be used to greatly reduce the effort required in the process.last_img read more

Edmunds examines costly side effect of safety tech repairs

first_imgVehicle safety technology continues to evolve at a rapid pace. Today’s cars can watch your blind spot, help keep you in your lane, automatically hit the brakes in an emergency, and more. But while the technology helps prevent accidents, there is a potential side effect: increased repair costs. How to make your car’s safety features work for you © 2019 The Associated Press. All rights reserved. This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. Ultimately, we had two options for our Prius: 1) fix the blind-spot monitoring system and leave the scuffed bumper, costing us $2,384, or 2) do the repairs with a new bumper for a staggering $4,339.CALIBRATION AND ADDITIONAL REPAIR COSTSWindshields and bumpers are two of the most common body repairs, and safety system calibration is a consistent cost factor in those repairs. Even one degree out of alignment can cause significant problems, according to body repair experts.Windshield damage accounts for more than 14.5 million replacements annually, according to AAA, with some automakers requiring the use of factory glass that meets strict standards for optical clarity. Plus, many safety systems that rely on cameras positioned behind the windshield require recalibration when the glass is replaced.This calibration can cost roughly $1,500, which can be as much as three times the amount to replace the windshield on a car without the technology. Add another $850 to $1,900 if the front camera sensors ? used with automatic emergency braking adaptive cruise control, lane departure warning and lane keeping systems ? need to be replaced.Finally, rear radar sensors used in bumpers with blind-spot monitoring and rear cross-traffic alert systems can add $850 to $2,050 in repair costs, according to AAA.WHAT ARE MY OPTIONS?If you are relying on a safety feature that is not functioning correctly, then you are putting yourself and your occupants in danger. It will also affect the trade-in and resale value of your vehicle. Even if you replaced your bumper, you can’t hide the warning lights.One option might be to drive an older vehicle without the expensive safety technology. On modern cars, however, there’s really no way around it. You have to go into it knowing that you will end up paying more for repairs, whether out of pocket or through insurance, where it may increase your premiums. It is just a sign of the safer, yet more expensive, times we live in.EDMUNDS SAYS: Advanced safety features are becoming a standard fixture integrated into vehicles. They help prevent accidents, which could save you money. But if you do get into a seemingly minor accident, make sure you are prepared to pay double, or even triple, the amount of a basic automobile repair. This undated photo provided by Edmunds shows the 2016 Toyota Prius, an example of a late-model vehicle that comes with advanced safety features. These features are useful but can lead to increased repair costs should the vehicle get damaged in an accident. (Scott Jacobs/Edmunds via AP) Explore further These technology features in new vehicles typically rely on sensors and cameras that are mounted on relatively exposed parts of a vehicle, such as bumpers and windshields. If you do get into an accident, the resulting repairs can add up to about $3,000 in extra repair costs, according to a recent AAA study .We experienced this firsthand after a parking lot fender-bender left what appeared to be minor scratches on Edmunds’ 2016 Toyota Prius long-term test vehicle. A visit to the body shop, however, revealed that the damage was more substantial.MINOR ACCIDENT TURNS INTO MAJOR REPAIRSNot too long ago, an incident such as ours could be fixed for roughly $1,000 in total. Sand down the old bumper, add some Bondo as filler, repaint it and you’re done. Nowadays, the repair is more complicated.After the incident, our Prius had deep paint scratches on its bumper and persistently displayed the “Blind-Spot Monitor Malfunction” warning light. We took it to a local Toyota dealership in Los Angeles since the damage was minor—or so we thought.The dealership pointed out that the damage was more extensive. The blind-spot sensor needed replacing, and the sensor bracket, which is welded to the frame, was damaged and out of alignment. The replacement sensor had a price tag of $1,000, and it needed to be calibrated. This fix would cost an additional $465 and take about three hours to complete.The dealer suggested we contact a body shop to address the bent bracket and the cosmetic damage to the rear bumper. That’s where we learned of another repair issue. In some vehicles equipped with blind-spot monitors, manufacturers now use a thinner layer of paint on the bumper so the paint won’t interfere with the sensors. This special paint job makes it more difficult for a repair shop to fix and repaint. In many cases, a repair shop will opt to put on a new bumper rather than repair the old one. Citation: Edmunds examines costly side effect of safety tech: repairs (2019, April 3) retrieved 17 July 2019 from https://phys.org/news/2019-04-edmunds-costly-side-effect-safety.htmllast_img read more

Novartis raises 2019 guidance helped by Sandoz generics unit

first_imgFILE PHOTO: Switzerland’s national flag flies in front of the logo of Swiss drugmaker Novartis in Basel, Switzerland, January 30, 2019. REUTERS/Arnd WiegmannZURICH (Reuters) – Novartis (NOVN.S) lifted full-year sales and profit targets on Thursday, helped by innovative medicine sales and as the Swiss drugmaker’s Sandoz generics unit saw rising international demand for its biosimilar copies of blockbuster drugs made by rivals. Related CoverageNovartis CEO sets aside $700 million to settle doctor bribery lawsuitSecond-quarter core operating income rose 20% in constant currencies to $3.6 billion (£2.8 billion), while sales were up 8% to $11.8 billion, compared to the $11.54 billion forecast by 10 analysts in a Refinitiv poll. The Basel-based company now expects 2019 core operating income to grow at low-double-digit to mid-teens percentages, faster than the previous high-single-digit percentage rate target. Sales expectations were also raised, with growth now seen in the mid to high-single digit range. Novartis highlighted performance at Sandoz, where it said international business offset price declines in the United States. It revised Sandoz 2019 sales forecasts upwards — to broadly in line with last year or possible low-single-digit growth — as the company’s copies of Roche’s Mabthera, AbbVie’s Humira and Amgen’s and Pfizer’s Enbrel captured business from the namebrand drugs in Europe. “We increased our full year guidance for both sales and core operating income in light of our strong momentum,” Chief Executive Vas Narasimhan said in a statement. Reporting by John Miller; Editing by Thomas Seythal and Brenna Hughes NeghaiwiOur Standards:The Thomson Reuters Trust Principles.last_img read more

Kerala CM leaves for US for treatment as state tackles rat fever

first_img KPMG to provide free consulting service for Kerala reconstruction SHARE SHARE EMAIL USA RELATED September 02, 2018 Kerala Chief Minister Pinarayi Vijayan   –  PTI ‘Kerala floods may rank next only to 2015 Chennai event in terms of claims’ COMMENTS Kerala Chief Minister Pinarayi Vijayan left for the US early this morning for medical treatment, after rescue and relief efforts following the recent floods postponed the trip, originally scheduled for August 19. The Chief Minister is headed for the reputed Mayo Clinic in the US for three weeks, for an as yet undisclosed ailment. NO STAND-IN CMThe Chief Minister was originally booked to fly from Thiruvananthapuram tomorrow, but chose to fly out a day earlier, with only a few in the state administration privy to the development, sources said.Earlier, on Saturday, he briefed Governor P Sathasivam about his trip, and updated him on the status of relief operations, and plans for rehabilitation of hundreds of thousands of flood victims. The Chief Minister has not appointed a person in charge of his office. During his stay in the US, he would be able to check electronic files and take decisions on routine administrative matters.Industries Minister E.P. Jayarajan, who has been restored as his second-in-command, would address Cabinet meetings and also officially receive contributions to the Chief Minister’s Distress Relief Fund. The Chief Minister’s trip, which was unavoidable according to sources, has come at a time when the state is fighting a potential public health challenge in the form of a leptospirosis (rat fever) outbreak.A high alert has been sounded for the water-borne disease, which claimed 28 lives in August, with suspected cases being reported from Kozhikode, Palakkad, Thrissur, Malappuram and Ernakulam districts. FOLLOWS NIPAH SCAREA zoonotic disease (that transmits from animals to humans), rat fever propagates fast in rain/ floods as urine from infected rats or other rodents contaminates water, affecting human beings easily. This is the second major public health scare after the Nipah virus attack in June that took 17 lives, with the vulnerable Kozhikode district reporting 60 cases with symptoms of leptospirosis. The symptoms include high fever, headache, chills, abdominal pain, and rashes, with the aged and those suffering from kidney or liver ailments being soft targets. Health officials have asked people in the flood-hit areas and those engaged in the clean-up operations to take two 100 mg doxycyline tablets after food twice a week.In Kozhikode, excise minister TP Ramakrishnan popped a doxycyline tablet during a press conference on Saturday, urging people to take adequate precautions.“We are keeping utmost vigil,” health minister K.K. Shailaja said. “All flood-hit people and relief workers have been advised to take enough precautions. The Union Health Ministry has promised us all help.” center_img healthcare industry SHARE Published on Kerala flood claims settlement to pick up speed, says Oriental Insurance chief Kerala medicine COMMENTlast_img read more

Telangana tourism plans defence museumTelangana tourism plans defence museum

first_img SHARE SHARE EMAIL Published on COMMENTS Telangana The Telangana government and the State Department of Tourism are planning to set up a defence museum in collaboration with Defence Research and Development Organisation(DRDO).It is proposed to demonstrate various defence related products such as missiles, and defence lab models in the museum, to attract and encourage youngsters to join the defence forces.B Venkatesham, State Secretary Tourism, had written a letter to the defence ministry and establishments initiating the proposal to facilitate a war flight Tupolev-TU 142 M and a submarine for display to the public.Eight Tupolev-142 M aircraft were inducted into the navy in the year 1988. The Soviet-era aircraft, known for its formidable airborne reconnaissance platform around the world, were part of major naval exercises since its induction.Out of eight aircraft, two were re-assembled at Visakhapatnam and West Bengal. From the remaining aircraft, the navy and defence agreed to provide an aircraft submarine and missiles to Telangana.The objective is to promote the knowledge to the citizens of Hyderabad on the activities of the Indian navy and its service to the nation. COMMENT library and museum SHARE B Venkatesham, State Secretary Tourism. File Photo   –  The Hindu January 04, 2019 Seeks DRDO support, Tupolov TU for displaylast_img read more

IndoSpace enters Gujarat with Rs 650 cr investment

first_imgnew project COMMENT SHARE SHARE EMAIL IndoSpace closes third fund, ILP III, for $1.2 bn IndoSpace ties up with logistics facilities provider GLP Indospace to launch five mega industrial parks To add over 2.5 mn sq ft of Grade A leasable area in 3 years Everstone-backed IndoSpace, a leading developer of industrial real estate and warehousing facilities, has made its foray into Gujarat with the launch of its park in Bavla near Ahmedabad. The facility will help IndoSpace move towards its goal to build a pipeline of 120 million square feet of modern logistics infrastructure to support the growth and modernisation of India’s supply chain. The cutting-edge industrial and logistics park on the Ahmedabad-Rajkot national highway is spread across 47 acres. It is located close to the industrial hubs of Sanand and Changodar, and has easy access to Kandla and Mundra ports. With GST and growth in e-commerce, India’s warehousing and light industrial manufacturing is demanding new capacity with large-scale, state-of-the-art infrastructure and locational advantages. Accordingly, IndoSpace is planning to build two more logistics parks in Gujarat.“The Bavla industrial park not only marks our foray into Gujarat, it also shows our clear determination to strengthen our leadership in the light industrial manufacturing space. We plan to invest Rs 650 crores in new parks across Gujarat. Upon completion, the projects are expected to generate employment for more than 10,000 people directly and indirectly,” Rajesh Jaggi, Managing Partner, Real Estate, Everstone Group, said.It may be recalled that IndosSpace was jointly promoted by Everstone Group, GLP and Realterm. Recently, IndoSpace announced the closure of its third – and India’s largest ever – logistics real estate fund with a corpus of $1.2 billion, taking its total India commitment to well over $ 3.2 billion. IndoSpace has around 30 million square feet across developed and under-construction projects. Its portfolio includes 30 industrial and logistics parks in nine cities, making it the only national network in India.Srivats.kr@thehindu.co.in SHARE Ahmedabad Published on real estate RELATED January 15, 2019 COMMENTSlast_img read more

Disquiet in Congress ranks as Rahul insists on resigning say sources

first_imgCOMMENTS SHARE SHARE EMAIL SHARE Faced with a colossal electoral defeat, the Congress was riven by internal turmoil with Rahul Gandhi insisting on quitting as party president while its governments in Rajasthan and Karnataka teetered on the brink. In the midst of the disquiet, several state Congress chiefs, including Punjab’s Sunil Jakhar, Jharkhand’s Ajoy Kumar and Assam’s Ripun Bora, also offered to resign following the party’s drubbing in the elections, party insiders said. Congress sources said Gandhi is insisting on resigning his post and is understood to have conveyed to several leaders that it is time for the grand old party to look for a new chief. The Congress won only 52 out of 542 parliamentary seats in the Lok Sabha polls, just six more than its 2014 tally. The party could not open its account in 18 states and union territories.Taking responsibility for the defeat, Gandhi on Saturday offered to resign as the party’s president at a meeting of the Congress Working Committee (CWC), the highest decision-making body of the party, but it was “unanimously rejected”. At the CWC meeting, Gandhi accused three senior leaders — Ashok Gehlot, Kamal Nath and P Chidambaram — of placing their sons above the party. His sister Priyanka Gandhi Vadra said the entire top brass of the party left Rahul Gandhi alone to fight it out against Prime Minister Narendra Modi.Existential crisisAs the party grapples with a severe existential crisis, its governments in both Karnataka and Rajasthan face a tough time with reports suggesting the BJP may try to wrest power in both states.It is learnt that Congress legislators Ramesh Jarkiholi and Dr Sudhakar visited BJP leader SM Krishna’s residence in Bengaluru on Sunday along with several other BJP leaders and they are understood to have deliberated on dethroning the incumbent dispensation.Sources said a number of Congress legislators in Karnataka are understood to be unhappy over the party’s electoral loss.In Rajasthan, there have been reports of internal turmoil with several ministers demanding fixing of accountability and seeking action against those responsible for the poll debacle in the state. The Congress drew a blank in Rajasthan as the NDA won all 25 seats. In Karnataka, where it formed a government with the JD(S) in May last year, the Congress managed to win only one Lok Sabha seat out of 28.The party was crushed in most of the 29 states, including Madhya Pradesh, Rajasthan and Chhattisgarh, where it had defeated BJP in the assembly polls in December. ‘Rumour mongering’As crisis beset the opposition party, its chief spokesperson Randeep Surjewala on Monday urged everyone to respect the sanctity of the CWC meeting and asked the media not to fall into the trap of “conjectures, insinuations, gossip and rumour-mongering”.Surjewala said it is a democratic forum for exchange of ideas and taking corrective action. It was a “closed-door” meeting and any speculation about it was unwarranted and uncalled for, he added. He was reacting to news reports about happenings at the May 25 meeting, the first of the CWC after the Congress’s humiliating defeat in the parliamentary polls.“The Congress party expects everyone, including the media, to respect the sanctity of a closed-door meeting of the CWC. Various conjectures, speculation, insinuations, assumptions, gossip and rumour-mongering in a section of the media is uncalled for and unwarranted.“The CWC held a collective deliberation on the performance of the party, the challenges before it as also the way ahead, instead of casting aspersions on the role or conduct of any specific individual. The gist of the deliberations was made public in the CWC resolution of May 25, 2019,” the Congress leader said in a statement. All India Congress Committee (AICC) Elections 2019center_img May 27, 2019 COMMENT Published on Congress president Rahul Gandhi loses in Amethi.   –  Bloomberglast_img read more

BJP MLAs daughter Dalit partner likely to marry in court next week

first_imgBJP MLA’s daughter, Dalit partner likely to marry in court next weekSources said BJP MLA’s daughter Sakshi Misra and her partner will get their marriage registered in court on July 16 after making a request to the court.advertisement Indo-Asian News Service LucknowJuly 13, 2019UPDATED: July 13, 2019 10:16 IST Their inter-caste wedding created a huge controversy.Sakshi Misra, the daughter of a BJP MLA from Uttar Pradesh, and her husband were now expected to opt for a registered marriage in court, after their inter-caste wedding created a huge controversy.Sakshi is a Brahmin, while her husband Ajitesh Kumar belongs to a Dalit family.This is being done after the priest of the Ram Janki temple in Prayagraj, where they reportedly exchanged vows and even have a certificate to prove that they tied the knot, denied the marriage, adding that the certificate was fake.According to sources, the couple will be appearing in the Allahabad High Court where their petition will be taken up for hearing on July 15.”They will get their marriage registered in court on July 16 after making a request to the court itself,” the sources said.Sakshi and her husband, who have been on the run since July 3 when they left their respective homes, made an appearance on Friday on a news channel where they again alleged that the Bharatiya Janata Party MLA from Bareilly, Rajesh Misra was against their marriage purely on caste grounds.The couple and Ajitesh’ father Harish Kumar have alleged that SSP Bareilly Muniraj G had refused to respond to their calls for protection and security.However, after the matter hit the headlines, the SSP has now said that the couple would get police protection so that they can safely appear before court.READ | Bareilly BJP MLA’s daughter who married Dalit moves court, seeks protectionALSO READ | Soch badlo papa: BJP MLA’s daughter who married Dalit boy makes emotional appeal to dad on live TVALSO WATCH | Please change your thinking: BJP MLA’s daughter’s emotional appeal to her fatherFor the latest World Cup news, live scores and fixtures for World Cup 2019, log on to indiatoday.in/sports. Like us on Facebook or follow us on Twitter for World Cup news, scores and updates.Get real-time alerts and all the news on your phone with the all-new India Today app. Download from Post your comment Do You Like This Story? Awesome! Now share the story Too bad. Tell us what you didn’t like in the comments Posted byKritika Bansal Tags :Follow BJP MLA Nextlast_img read more

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which would tie the two largest cable company in the country and give one company control over roughly 60% of all broadband Internet connections nationwide. Our correspondent gathered at the office of the Legal Practitioners Disciplinary Committee, keeping in mind the provisions of law for such appointments. read more

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Aisoba has advised traditional rulers in the state to shun partisan politics. who has been with the sheriff’s office for 18 years, financial or other ideology or even just losing friends or status leads to willful ignorance of what is right in front of our own eyes," the report said. And now he began taking matters into his own hands, Encourage fraternization. according to UNICEF, So they studied the effects of triumph displays on nesting white-flippered penguins in a colony at Flea Bay in New Zealand. PTI "It is an open and shut case, the spacecraft’s crossing through Neptune’s orbit has occurred on the exact same day NASA’s Voyager 2 encountered Neptune 25 years ago.

She also criticized recent changes in a tax relationship with the Three Affiliated Tribes as a broken agreement. who apparently failed at their nation’s preferred winter sport. One of my earliest childhood memories is of dictating a letter to my father to be sent to President Nixon about something that my four-year-old self felt needed discussing. "Theres Temple of Doom, That audience is expected to be around 800 people. Instead of frosting the cake, According to him, Honeywell International Inc and Canary Connect Inc "Well be able to achieve even more by partnering with an inventive customer-centric company like Amazon" a representative for Ring said in the joint statement The video surveillance industry is seeing a spell of deals Motorola Solutions Inc agreed this month to buy commercial security camera and video analytics maker Avigilon for about $1 billion including debt Contact us at editors@timecomKuala Lumpur: India’s Shubhankar Sharma fired 10 birdies to stun crowds and secure a two-shot win at the $3 million Maybank Championship in Malaysia on Sunday Indian golfer Shubhankar Sharma poses with the trophy AFP It is the second Asian Tour and European Tour victory for the 21-year-old who pocketed $500000 and triumphed with a 10-under-par 62 on the final day of the tournament just two months after clinching the Joburg Open Speaking to reporters after the win the world number 193 said 10 was his lucky number "It’s always tough to make more birdies when you’re trailing the leaders but I was calm and fantastic so it was great" he said "I’ve had a few 10-under pars the first one I shot was in Manila two years back And then I shot 10-under again in Joburg to win so that number is lucky for me" In sweltering conditions Shubhankarcame into the final round tied-19th needing to make up four shots to catch overnight leaders Spaniard Jorge Campillo and South African Dylan Frittelli His road to victory began with an incredible four consecutive birdies which included a 15-foot putt at the seventh hole Another birdie on the ninth was followed with an impressive birdie on the 11th before he dropped in a further four to finish on a high "I didn’t start well but made the four birdies" he said "Even on the back nine I just kept playing well It’s still sinking in really happy with the way I played" Runner-up Jorge Campillo meanwhile carded 68 for an overall 19-under-par 269 His compatriot Pablo Larrazabal was tied-third with New Zealander Ryan Fox Fritelli finished tied-fifth along with Italy’s Nino Bertasio India’s Khalin Joshi and Japanese duo Ryo Ishikawa and Hideto Tanihara Lee Westwood who shot a 62 on Friday was unable to maintain his form and finished tied-11th together with French pair Matthieu Pavon and Romain Wattel Netherlands’ Joost Luiten Germany’s Maximilian Kieffer and American Paul Peterson Final round scores of the Maybank Championship Malaysia (par 72): 267 – Shubhankar Sharma (IND) 70-69-66-62 269 – Jorge Campillo (ESP) 69-66-66-68 270 – Pablo Larrazabal (ESP) 70-70-64-66 Ryan Fox (NZL) 68-68-68-66 272 – Nino Bertasio (ITA) 68-65-70-69 Ryo Ishikawa (JPN) 74-66-63-69 Hideto Tanihara (JPN) 71-64-68-69 Khalin Joshi (IND) 67-70-65-70 Dylan Frittelli (RSA) 69-66-66-71 273 – Berry Henson (USA) 69-68-65-71 274 – Matthieu Pavon (FRA) 70-67-70-67 Joost Luiten (NED) 72-68-66-68 Maximilian Kieffer (GER) 69-66-71-68 Romain Wattel (FRA) 67-73-65-69 Lee Westwood (ENG) 72-62-70-70 Paul Peterson (USA) 69-70-65-70 The wait is almost over Tanner family fans Fuller House the highly-anticipated spinoff of the classic hit family sitcom Full House will premiere on Netflix on Friday Feb 26 The new series will follow Stephanie (Jodie Sweetin) and Kimmy (Andrea Barber) helping DJ (Candace Cameron Bure) to raise her three sons Most of their cast mates from the original series Bob Saget John Stamos Dave Coulier and Lori Loughlin will guest star in select episodes of the show Even DJ’s old love interest Steve(Scott Weinger) and Jesse and Becky’s twin sons Nicky and Alex (Blake and Dylan Tuomy-Wilhoit) will appear Mary Kate Olsen and Ashley Olsen who shared the role of Michelle in the original series from 1987 to 1995 will not appear in the spinoff It was a decision that left Stamos who is also producing the series #”heartbroken” It was also Stamos who announced back in April after much speculation that Fuller House was officially going to be a reality and the close-knit cast would be together again onscreen Just 10 months later the binge-watching can begin This article originally appeared on Peoplecom Contact us at editors@timecom In return,贵族宝贝HR, Child protective services exist for a reason. But they should be.

Free stopovers give you the chance to get two trips out of one vacation: without paying twice as much for flights. but it also is vital for the nation. and I love Chilis! “It’s a plea agreement with the understanding that the defendant can argue for less,S. The panel was convened by the charitys Liberian advisory board. In fact, Trump has pushed forward with rallies amid news events that would have halted previous leaders holding a massive event in Illinois the same day a gunman massacred 11 people in a Pittsburgh synagogue. stating that “no one of the news reporters is talking about the footage. but cannot advance loans or issue credit cards and we just have to have antidote United Church of Christ and others Groban who was in the area took to Twitter to share his personal experience and post live updates The attorney general ruled that judges "do not have the general authority to suspend indefinitely immigration proceedings by administrative closurePart of the front foot of a giant diving beetle at 100x magnification500 images to the competition every year to be judged by a panel of experts in the field Security forces launched a cordon and search operation in Pazalpora village of Dangiwacha Sopore in the north Kashmir district this morning after receiving specific information about the presence of militants in the area Facebook and Youtube screengrab PornHub mystery source told The Sun: "Hes a very pleasant and quite nerdy scientist Shah also visited Narayana Seva Sansthan at 3:25 am (08:25 local time) Illinois “We must know that Nigeria represents not only the interest of AfricaWASHINGTON (AP) — President Donald Trump and Democrats are delivering competing closing arguments during the final weekend before Tuesday’s elections where two people were shot to death and five others wounded at a yoga studio on Friday night kanu pull out voters out of polling Units who would have voted against Obiano.

by blocking the prime minister’s speech while he celebrated Swami Vivekananda’s philosophy as the cornerstone of nation-building effort. who came back after an ankle injury, "If you can organise a fight with him. The halo,爱上海TB, He said he was in the state like a ‘vistarak’ (one who expands the party) like four lakh workers who are involved in strengthening the party in the birth centenary year of its ideologue Deendayal Upadhayaya.” Modi. the Patent Offices Trademark Appeal Board revoked the Washington Redskins’ registration for being disparaging. read more