Big Pharma prices soar, Part 2

first_imgLifesaving medications, including Harvoni which can cure hepatitis C, are often developed through taxpayer-funded research. But they are priced out of reach for most of the people who need them. There are no laws or other restrictions to stop pharmaceutical companies from charging whatever they can get away with. And they count on Medicaid and Medicare to pick up the bill.While the December 2016 findings of the U.S. Senate Special Committee on Aging should clearly be grounds to indict the CEOs of pharmaceutical companies responsible for price gouging, the odds are against this ever happening. (For names of offending companies, see Part 1 in Jan. 5 WW.)Since 1959 the U.S. Congress has held over 50 separate hearings to investigate the pharmaceutical industry. All have reached pretty much the same conclusion: Pharmaceutical companies are maximizing their profits at the expense of the public.Despite all these hearings, at who knows what cost, Congress has yet to pass any legislation that would restrict pharmaceutical companies from charging whatever they want. Nonetheless, the hearings go on and on.In 2014 the Senate Subcommittee on Primary Health and Aging held a hearing to investigate steep and unexpected price hikes on some generic drugs. But the cost of many generic drugs has continued to skyrocket.In 2015 the U.S. Congress held hearings to investigate Gilead Sciences for raising the cost of drugs, including Harvoni. The investigation concluded that the only explanation for the high costs was the company’s greed: Gilead was charging as much as it could get away with for the drug because it could.Early in 2016 the House Committee on Oversight and Government Reform called Mylan CEO Heather Bresch to testify after the outrageous rise in the price of the lifesaving EpiPen. While Mylan has now lowered the cost, it still remains significantly higher than what is charged outside the U.S.In December 2016, the U.S. Justice Department brought criminal charges against two pharmaceutical executives for conspiring with other drug makers to fix generic drug prices. The DOJ charged former pharmaceutical executives Jeffrey A. Glazer and Jason T. Malek with colluding over the course of seven years with “unnamed brand-name corporations and individuals” to fix prices and rig bids on drugs used to treat bacterial infections, acne and diabetes.Six pharmaceutical companies are currently under investigation for conspiring to fix prices of generic medicines under a civil action filed by 20 states. News of these investigations sent pharmaceutical stocks tumbling, but odds are it’s a temporary setback.U.S. gov’t policies promote higher drug pricesWhen the House Committee on Oversight and Government attempted to question Martin Shkreli in 2015 over the dramatic price increase of Daraprim, he refused to answer any questions other than explaining how to pronounce his name. After repeatedly taking the Fifth Amendment against self-incrimination, Shkreli later expressed his disdain for the process in a Twitter post: “Hard to accept that these imbeciles represent the people in our government.”While his contempt of Congress comes from the point of view of people in the billionaire class that Congress actually protects, in a way Shkreli underscored an important problem: The U.S. remains the only developed country with no real oversight to restrict what drug companies can charge the public.Prescription drugs can be found at lower prices — outside the U.S. In Egypt Harvoni costs $10 per pill. Daraprim can still be purchased in Britain for 66 cents a pill and costs even less in India. An EpiPen two-pack can be purchased at a pharmacy in Canada for $145 and in Britain for $69. If you didn’t live in the U.S., you could buy all these drugs and more from other countries for far less.However, the U.S. Food and Drug Administration makes it very difficult for individuals to import prescription drugs for personal use unless the drug is for a serious condition and not available in the U.S. Even then, no more than a three-month supply can be imported.Congress passed the Prescription Drug Marketing Act (PDMA) in 1987 prohibiting anyone other than U.S. pharmaceutical manufacturers from importing prescription drugs. Some states have recently required doctors to electronically send prescriptions to pharmacies instead of giving written prescriptions to patients, making it harder for them to seek lower prices.Profits before people remains the governing principle that dictates U.S. policies. The U.S. is the only country that allows pharmaceutical manufacturers to set drug prices with no limitations.As of this writing, one of two people being vetted as the next Food and Drug Administration commissioner is Jim O’Neill, a managing director at Mithril Capital Management, run by one of Donald Trump’s billionaire donors and advisors. O’Neill has suggested that the FDA let drug companies put products on the market before proving they work. They just have to be “safe” before being sold. O’Neill’s take on new drugs: “Let’s prove efficacy after they’ve been legalized.”This is after passage of the 21st Century Cures Act under the Obama administration, which has already undermined patient safety by requiring less restrictive testing before drugs are marketed.Whether Trump appoints O’Neill or another billionaire, it’s clear that the end game won’t be to improve conditions for working and poor people. Untested and potentially unsafe new drugs are not the solution to the health crisis caused by exorbitant prices. The prescription called for is to eliminate the capitalist profit drive behind this crucial industry.FacebookTwitterWhatsAppEmailPrintMoreShare thisFacebookTwitterWhatsAppEmailPrintMoreShare thislast_img read more

Early Childhood Matters class aims to improve early education in Fort Worth

first_imgNew food truck joins Blue Zones Project Twitter TAGSchildrenFort Worth libraryliteracy rateparenting Forth-Annual Fort Worth Earth Party Libby Vincekhttps://www.tcu360.com/author/libby-vincek/ Twitter + posts Facebook ReddIt Previous articleNutrition students promote food safety as summer approachesNext articleJimmy Tatro talks ambitions of a college dropout Libby Vincek RELATED ARTICLESMORE FROM AUTHOR Libby Vincekhttps://www.tcu360.com/author/libby-vincek/ Linkedin Libby Vincek center_img ReddIt Abortion access threatened as restrictive bills make their way through Texas Legislature Libby Vincekhttps://www.tcu360.com/author/libby-vincek/ Facebook Libby Vincekhttps://www.tcu360.com/author/libby-vincek/ Linkedin Grains to grocery: One bread maker brings together farmers and artisans at locally-sourced store The Wandering Boutique printStudents leaned forward listening to their teacher lecture in both English and Spanish at the front of the classroom. Pens scratched over notes while toddlers played with tablets and puzzles down the hall.In the Early Childhood Matters program, the parents are the students.The program, run by the Fort Worth Library Youth and Teen Division, teaches parents techniques to better their child’s capacity to learn and relate their emotional needs. The program hosts three 10-week series throughout the year.The first 10-week series focused on four subjects:Intro to Brain Development: Ages and Stages of Child DevelopmentDiscipline: Guidance/Positive Discipline-Approaches and PrinciplesCommunication in the FamilyDiscussions of School ReadinessThe second and third series are subject to change based on the reactions and results from the first series.Early Childhood Matters (ECM) approaches educating families based on community research collected by UTA and Dr. T. Berry Brazelton’s Touchpoints practice and principles. This program helps instructors and staff understand how to work with families and support them at vital stages of their child’s development.The program has been hosted in community centers and library branches throughout Fort Worth for 10 years. It has 10 locations in Fort Worth.Minerva Gates, an ECM coordinator, said the program preps attendees for parenting by helping them understand childhood development.Zero to Three, a nonprofit organization and resource for the ECM curriculum, says that 85 percent of children’s brains are developed before they are three years old. The nonprofit also says that children’s success in school and in life improve when their adult caregivers’ knowledge, skills and behaviors are based in an understanding of how children grow and learn in the early years.“Parents are children’s first and most important teachers,” Gates said.One of the classes at the Worth Heights Neighborhood Center teaches predominantly Spanish-speaking families to work with their children. A public educator for ECM, Victoria Capik, teaches five classes a week in multiple locations in both English and Spanish.Capik, who has taught for ECM for over six years, said she knows the value of teaching kids early no matter the language barrier.“Depending on the locations of where the child is raised, their parents aren’t aware of what their child needs in order to be able to enter school with confidence,” Capik said.Many families in Fort Worth face a language barrier when trying to teach their children before sending them to public schools. Gates said ECM strives to help those families by providing instructors who can bridge language gaps.Gates added that teachers like Capik make their program special.“Victoria’s passion resonates in the community because she has the ability to empathize with the child and help the loving adult see why it’s important to be the child’s first teacher,” said Gates.Capik instructed parents on positive reinforcement and discipline. She translated in English and Spanish.Gates said a child’s school readiness is important and parents play a key role. They will apply helpful behaviors, she said, when they know what to do and are encouraged by their community.The program is free for parents and children. The city funds approximately $750,000 for the salaries of five specialists and the coordinator. It also pays for books given to families at each session, snacks for children, operating supplies and tablets for the children to use during parents’ class time.Capik said that this program is more than just a class. Their budget also provides their children with books they can keep.The books are gifts to parents and children from the program in order for them to not only exercise their reading skills, but also practice the specific lessons the class has focused on.Hear what else Capik had to say about establishing reading habits early on.This is one of the many ways ECM encourages learning for children in the program.Michelle Lee is an early learning specialist assigned to the children programming of ECM. She develops age appropriate activities for the program, oversees children’s engagement in said activities and helps develop training for the child care aids.Lee describes how the programs the children learn through playtime tie into the state educational guidelines so there is more “intentional learning.” Parents are also able to learn about the certain apps and techonology their children will be exposed to when they enter school. She says that it is important for children and parents to use the technology together.“Technology is a part of our lives now and forever on, and it’s also in the Pre-K learning guidelines so we’re helping them meet that need before they get to kindergarten,” Lee said.Tablets are one of the many education tools child care aids use with children in the program.Maricela Mendoza, a child care aid, said that watching the progress of the children from series one until they enter kindergarten has been “a special gift that is hard to explain.”One parent talked about the progress her family has made through in the Early Childhood Development program.“I learned how to help my child be more independent. I was doing everything for her not realizing I was not helping her development but rather delaying it,” a parent said.Capik said she’s fortunate to work with these families and see them grow.“They went from the uncertainty of what the first step into education is to now the potential of what their child can become and what colleges they can attend,” she said. Fort Worth Junior League sells programs for charity at Stock Show Fort Worth set to elect first new mayor in 10 years Saturdaylast_img read more

Research In Motion under pressure to give access to BlackBerry user data

first_img News April 28, 2021 Find out more Saudi ArabiaMiddle East – North Africa Organisation RSF_en March 9, 2021 Find out more Saudi ArabiaMiddle East – North Africa Reporters Without Borders condemns the suspension of BlackBerry instant messaging services announced by Saudi Arabia, where it was due to begin today, and by the United Arab Emirates, where it is due to begin in October. Indonesia, India, Egypt and Kuwait have also voiced concern about BlackBerry’s encrypted services and have asked its Canadian manufacturer, Research in Motion (RIM), to give them access to users’ confidential data.The Indonesian authorities yesterday denied that they were considering the possibility of blocking any BlackBerry services but said they wanted RIM to set up a data routing centre inside the country. Having the data in Indonesia would mean any issues could be referred to the country’s courts.“The ‘national security’ argument is just a pretext,” Reporters Without Borders said. “What really bothers the countries that use this pretext is their inability to monitor BlackBerry’s services. Many of these countries have already adopted a wide range of Internet censorship measures. BlackBerry is their latest target because it is being used for discussion and debate and, as such, needs to be censored as well. Those most affected will be BlackBerry users in these countries, who will find they have even less scope for free expression.”The Indian daily The Economic Times reported on 2 August that RIM was ready to decrypt certain kinds of data and pass them on to the Indian intelligence services. RIM has meanwhile issued several statements denying that it passes on information to countries such as the United States (as the Emirati authorities have claimed) and promising to respect both government regulations and the security and data protection needs of companies and consumers.BlackBerry encrypts its services better than most smartphone manufacturers do, and RIM has refused to provide the access codes that would allow governments to monitor the content of encrypted messages. Monitoring is impossible because a system of keys available only to users guarantees data confidentiality.Reporters Without Borders secretary-general Jean-François Julliard wrote to RIM founder and co-CEO Mike Lazaridis on 4 August urging him not to yield to pressure and to guarantee data confidentiality. The press freedom organisation also wrote to the Saudi and Emirati authorities asked them to refrain from suspending its services and thereby avoid dealing a serious blow to free expression.The United Arab Emirates and Saudi Arabia claim that BlackBerry’s services break their laws and threaten national security. The UAE’s Telecommunication Regulatory Authority has announced that it will suspend BlackBerry’s instant messaging, email, web browsing and roaming services from 11 October.The UAE is ranked as a “country under surveillance” and Saudi Arabia is ranked as an “Enemy of the Internet” in the latest Reporters Without Borders report on online free expression, which was released on 12 March. Help by sharing this information RSF joins Middle East and North Africa coalition to combat digital surveillance NSO Group hasn’t kept its promises on human rights, RSF and other NGOs saycenter_img to go further August 6, 2010 – Updated on January 20, 2016 Research In Motion under pressure to give access to BlackBerry user data June 8, 2021 Find out more News Receive email alerts News News Saudi media silent on RSF complaint against MBS Follow the news on Saudi Arabialast_img read more

Meow Meow to the Rescue

first_imgCommunity News Meow Meow to the Rescue Father of daughter that drowned at unlicensed summer camp records touching video to child and her favorite pal By DONOVAN MCCRAY Published on Tuesday, March 31, 2020 | 5:00 am EVENTS & ENTERTAINMENT | FOOD & DRINK | THE ARTS | REAL ESTATE | HOME & GARDEN | WELLNESS | SOCIAL SCENE | GETAWAYS | PARENTS & KIDS Get our daily Pasadena newspaper in your email box. Free.Get all the latest Pasadena news, more than 10 fresh stories daily, 7 days a week at 7 a.m. <span data-mce-type=”bookmark” style=”display: inline-block; width: 0px; overflow: hidden; line-height: 0;” class=”mce_SELRES_start”>?</span>The Journey of SuperMeow from D.A. Forbes on Vimeo.Doug Forbes and his wife Elena Matyas have filmed a visual love story to their daughter Roxie and her favorite stuffed animal Meow Meow.Roxie drowned at Summerkids an unlicensed summer camp in Altadena on June 28.“Meow Meow Foundation would like to share this VERY raw visual love letter with you. Maybe we can all feel a little better, smile, laugh, even cryin a good way,” Forbes said in an email to Pasadena Now.“It’s also a sneak peek into what will eventually become a book series.”Roxie entered the camp pool June 28 at about 9:25 a.m., accompanied by a counselor. About ten to fifteen minutes later, another counselor who wasworking with other campers about thirty to forty-five feet outside the gate of the swimming pool was the first person to finally notice Roxiefloating face down in the pool, the suit says.State documents show the California Dept. of Social Services substantiated two allegations that Summerkids has operated without a required licensewhich the state says “poses an immediate health, safety or personal rights risk to children in care.”The family has teamed with state Sen. Anthony Portantino, who has introduced Senate Bill 955 – “the Roxie Rules Act,” which seeks to address whatPortantino acknowledged is “a deficiency in camp licensing, inspection, and oversight.’’The state Department of Social Services and Attorney General Xavier Becerra are seeking an injunction that would prevent Altadena’s Summerkids fromopening.The video can be viewed at meowmeowfoundation.org/news/supermeow-the-journey Business News Home of the Week: Unique Pasadena Home Located on Madeline Drive, Pasadena CITY NEWS SERVICE/STAFF REPORT Pasadena Will Allow Vaccinated People to Go Without Masks in Most Settings Starting on Tuesday STAFF REPORT Pasadena’s ‘626 Day’ Aims to Celebrate City, Boost Local Economy Community News Community News Make a commentcenter_img More Cool Stuff Top of the News STAFF REPORT First Heatwave Expected Next Week Subscribe Your email address will not be published. Required fields are marked * Name (required)  Mail (required) (not be published)  Website  faithfernandez More » ShareTweetShare on Google+Pin on PinterestSend with WhatsApp,Donald CommunityPCC- COMMUNITYVirtual Schools PasadenaHomes Solve Community/Gov/Pub SafetyPasadena Public WorksPASADENA EVENTS & ACTIVITIES CALENDARClick here for Movie Showtimes 39 recommended0 commentsShareShareTweetSharePin it Herbeauty12 Signs He’s Ready To Spend The Rest Of His Life With YouHerbeautyHerbeautyHerbeautyIs It Bad To Give Your Boyfriend An Ultimatum?HerbeautyHerbeautyHerbeautyAmazing Sparks Of On-Screen Chemistry From The 90-sHerbeautyHerbeautyHerbeautyTop 9 Predicted Haircut Trends Of 2020HerbeautyHerbeautyHerbeautyThese Are 15 Great Style Tips From Asian WomenHerbeautyHerbeautyHerbeautyYou Can’t Go Past Our Healthy Quick RecipesHerbeautyHerbeautylast_img read more

Learning for life: Stress management

first_imgLearning for life: Stress managementOn 1 Oct 2002 in Personnel Today Comments are closed. Life Long Learning and Continuing Professional Development (CPD) are theprocesses by which professionals, such as nurses, develop and improve theirpractice. There are many ways to address CPD: formally, through attending courses,study days and workshops; or informally, through private study and reflection.Reading articles in professional journals is a good way of keeping up-to-datewith what is going on in the field of practice, but reflecting and identifyingwhat you have learnt is not always easy. These questions are designed to helpyou to identify what you have learnt from studying the article. They will alsohelp you to clarify what you can apply to practice, what you did not understandand what you need to explore further. 1.What percentage of European Union workers experience stress at work? a) 48 b) 38 c) 28 d) 58 2. Who needs to be involved in policy development? a) Managing director b) Stakeholders c) Line managers s) Experts 3. What sort of committee needs to be established? a) Steering b) Standing c) Health and safety d) Sub-committee 4. What sort of approach should the committee take? a) Authoritarian b) Utilitarian c) Liberal d) Democratic 5. Which of the following is NOT an objective of the stress policy? a) To communicate commitment b) To raise awareness c) To decide blame d) To clarify roles 6. The implementation of a stress policy should be facilitated in whichthree ways? a) Communicated, supported, business procedures b) Communicated, supported, management and staff accept responsibilities c) Communicated, business procedures, management and staff acceptresponsibilities d) Business procedures, supported, management and staff accept responsibilities7. Which is NOT the way for longer-term effects of the policy to beassessed? a) Changes in rates of absence related to stress b) Performance c) Use of counselling services d) Use of disciplinary procedures 8. Who should be encouraged to take ownership of the policy? a) Management and staff b) Occupational health c) Health and safety officer d) Personnel 9. Which is NOT a stage of policy development in this article? a) General principles b) Partnership approach c) Selling the policy d) Writing the policy 10 What should be carried out once the policy has been implemented? a) Risk assessment b) Audit c) Evaluation d) Planning Feedback1.c).2.b) List who in your workplace has an interest and therefore a stake in astress policy and identify who would be best to represent their interests on apolicy development committee. 3.a) Write short notes on what youunderstand about each different type of committee. If you are not sure of allthe different types of committees, carry out a search for this information. 4.d)All these words sound quite plausible, but answers a, c and b are allleadership styles and b is a branch of moral philosophy! Look up each one andensure that you understand them and their differences. 5.c) Today’ssociety is very much a ‘blame’ culture. However, there are efforts to move awayfrom this in the workplace. Discuss this with your colleagues. 6.b). 7.d)See answer to question 5. 8.a) Although this article is about developinga policy for managing stress, it is also about developing policies per se.Think how policy development follows the quality assurance and problem-solvingmodels of assess, plan, implement and evaluate. More about this can be found inmany publications but the HSE’s Successful Health and Safety Management 1997deals with this topic in depth. 9.d) Of course all these stages are partof policy development but this stage has not been mentioned in the article! 10.c)The article actually says ‘evaluation’ but audit would have been correct too.No policy is worth having unless its effectiveness is measured from time totime. What policies does your organisation have? How often are they reviewed?What information is required to monitor their effectiveness? Consider what you cando to improve the situation if it is not up to standard. Related posts:No related photos. Previous Article Next Articlelast_img read more

EXCLUSIVE: Jeremy Corbyn, Jackie Weaver and more to speak at the Oxford Union

first_imgJeremy Corbyn, Jackie Weaver, and Jed Mercurio will be amongst the line-up of this term’s speakers at The Oxford Union, alongside other speakers including designer Diane Von Furstenberg, former Liberal Democrat leader Sir Vince Cable, and Alayo Akinkugbe, founder of @ABlackHistoryOfArt. Events will take place online until the 17th May when the Union hopes to organise some socially distanced in-person speaker events.Corbyn is the former leader of the Labour party and was temporarily suspended after stating that he believed the issue of antisemitism in the party had been “dramatically overstated,” although he has since been reinstated to a role as an independent MP. Jackie Weaver made headlines after her appearance in the viral Handforth Parish Council Zoom meeting, during which she kicked off one of the councillors and was told to “read the standing orders.” Further speakers in the line-up include Professor Julian Stallabras, art historian and curator, British athlete Dwain Chambers, and Soma Sara, who founded Everyone’s Invited, an online movement seeking to eradicate rape culture. Speakers that are still to be confirmed include Mamma Mia! star Lily James, supermodel, actress and filmmaker Lily Cole, Michael Eavis, dairy farmer and creator of the Glastonbury Festival, and footballer Virgil van Dijk. The Union will also be hosting a range of panel events, including ‘This House Would Abolish the Monarchy,’ which will feature, amongst others, British Military Commander Lieutenant General Arundell David Leakey alongside curator Anne Pasternack. Other panels include ‘This House Believes Veganism is the Only Ethical Choice,’ ‘This House Believes We Must Urgently Rewrite History,’ and ‘This House Believes the European Project is Doomed to Fail.’ Adam Roble, President of the Oxford Union, told Cherwell: “It has been an absolute honour to work on this term-card, and I hope members will find that there is something for everyone in it. Being the first black President of the 21st century coupled with being an access member of the Union, accessibility and the ensuring of a welcoming yet relevant space for absolutely all of its members is at the core of what has driven the nature of this termcard. This is something that will always be one of my highest priorities. “When I ran I made several pledges to the members, from holding a review into the Union’s diversity to hosting a varied range of socials. Ultimately actions speak volume and I hope this termcard demonstrates a Union that hosts the conversations that matter, and yet ignites independent thought across the membership.”“After a busy term of eight debates, several speakers events a week and a hugely exciting calendar of more social events than ever before, I hope that we will all be able to look back in 8th week on this term with pride. I hope that we will all see a Union getting closer to what it ought to be. A place for debate, inclusion, and crucially joy. A huge thank you to the committee for building this termcard. I wouldn’t have been able to do it without you all.”Image Credit: Jeremy Corbyn / CC BY 2.0last_img read more

Gov. Holcomb warns young Hoosiers to wear face masks

first_img WhatsApp (Photo supplied/State of Indiana) Young people who are not social distancing or wearing masks are catching flack from Indiana Governor Eric Holcomb.He and state health commissioner Dr. Kristina Box says 30 percent of positive cases of coronavirus are young people, up from 12 percent in March.Don’t let your state lose ground, was the message from Governor Holcomb during his weekly COVID-19 news conference on Wednesday, June 24. Holcomb said some young people are guilty of not social distancing and not wearing masks in public.The Governor encouraged young Hoosiers to “do the right thing” for themselves and older people who you may come into contact with.Dr. Box said the coronavirus recovery rate is up in Indiana and the number of people in hospitals has gone down. She said that was encouraging as the state continues to open back up.However, at least one local hospital is as busy as ever dealing with COVID-19. Goshen Health issued the following statement on Wednesday:COVID-19 activity for Goshen Health as of June 24. Testing:7,745 tests completed1,054 positive test results (overall positivity rate of 14.3%)6,304 negative test resultsTest results outstanding: 373 Hospitalizations:Admitted 133Discharged 118Confirmed 10 COVID-positive related mortalities“Our Urgent Care and Emergency Department Colleagues have faced several weeks of extremely high volumes. Plus, last week our overall census was much higher. Colleagues are fatigued, but remain dedicated to serving our community,” said Randy Christophel, President and CEO of Goshen Health. “We continue to ask our community to show support for our local healthcare providers, support staff and each other by taking every precaution possible, starting with wearing a mask in public,” said Dr. Dan Nafziger, Hospital Chief Medical Officer. “Physical distancing, handwashing, disinfecting and staying home if you’re not feeling well – all of these continue to be important for everyone’s protection. As we are getting back into more activities with people outside of our immediate households following these safety precautions has never been more important.” Gov. Holcomb warns young Hoosiers to wear face masks Twitter WhatsApp Facebook Pinterest CoronavirusIndianaLocalNews Google+ By Jon Zimney – June 25, 2020 0 414 Facebook Google+ Previous articleSome Hoosiers overpaid unemployment benefits, state wants money backNext articleHolcomb announces $25M in relief funding for Indiana renters Jon ZimneyJon Zimney is the News and Programming Director for News/Talk 95.3 Michiana’s News Channel and host of the Fries With That podcast. Follow him on Twitter @jzimney. Twitter Pinterestlast_img read more

Peter Frampton & Gregg Allman Join Forces For Indy Throwdown [A Gallery]

first_imgThere’s nothing quite like the opportunity to see a music legend at work. So many individuals have given themselves to the art of performance, but only a choice few can maintain longevity and stand the test of time. Last night at the Farm Bureau Insurance Lawn in Indianapolis, IN, not one but two legends performed for an enthusiastic crowd. Those legends were, of course, Peter Frampton and Gregg Allman.Frampton has enjoyed a successful career, powered by hits like “Show Me The Way” and “Do You Feel Like We Do?” There’s no slowing down for the rocker, as he treated fans to a great celebration of his music. Allman, too, has shown no signs of slowing down, even though his band The Allman Brothers shut down after their 45th anniversary in 2014. His new solo act is top-notch, bringing fans a potent mix of ABB hits, blues standards, and more.Thankfully, Phierce Photo was on the ground to capture this classic rockin’ scene. Check it out below! Load remaining imageslast_img read more

Mother of Peanut

first_imgWorking to understand the genetics of peanut disease resistance and yield, researchers led by scientists at the University of Georgia have uncovered the peanut’s unlikely and complicated evolution.Researchers working as part of the International Peanut Genome Initiative have previously pinpointed one of the peanut’s two wild ancestors and shown that the peanut is a living legacy of some of the earliest human agricultural societies in South America. Since then the team has mapped the entire peanut genome and identified the crop’s second wild ancestor and the novel mechanism by which the shy, seed-hoarding plant generated the diversity we see today.“Because of its complex genetic structure, sequencing peanut was only possible using very recent developments in sequencing technology. The result is of unprecedented quality, and provides a reference framework for breeding and improvement of the peanut crop, and a whole new set of insights into the extraordinary genetic structure of peanut,” said David Bertioli, Georgia Research Alliance Distinguished Investigator and peanut researcher at the College of Agricultural and Environmental Sciences.Bertioli conducts his research through the CAES Institute for Plant Breeding, Genetics and Genomics, which is home to some of the world’s foremost experts in this area of crop science and has been prolific in providing new genomic tools and information to help plant breeders around the world develop more sustainable, productive crop varieties.The team’s most recent paper was published in the journal Nature Genetics and is available at doi.org/10.1038/s41588-019-0405-z.According to the U.S. Department of Agriculture, farmers around the world grow 44.9 million metric tons of peanuts on more than 64 million acres. The crop is a staple food in many parts of Africa and Asia and is a source of peanut butter, snacks and cooking oil in the U.S. In Georgia alone, farmers grow $825 million in peanuts each year.Despite their importance as a crop, plant researchers haven’t had many of the genetic tools needed to speed up the introduction of more sustainable and productive peanut varieties. That was because, until recently, scientists had been unable to map the peanuts’ hypercomplex tetraploid genome. The Peanut Genome Initiative’s international collaboration and advancements in technologies and data processing yielded the breakthroughs.Peanut genome sequencedThe bedrock of the team’s discoveries was the sequencing of the genome. Because the peanut originated from the hybridization of two wild ancestral species thousands of years ago, the initial phases of the project involved researchers developing genome sequences for those ancestors. Together, the ancestral genomes made a prototype for the genetic structure of cultivated peanuts. This was published in 2016 at nature.com/ng/journal/vaop/ncurrent/full/ng.3517.html.This month, the Peanut Genome Initiative discussed the entire genome sequence for the modern cultivated peanut in a paper called “The genome sequence of segmental allotetraploid peanut Arachis hypogaea.”The researchers used new advances in DNA-sequencing technologies to produce a complete genome sequence of unprecedented quality. The sequence consists of more than 2.5 billion base pairs of DNA arranged in 20 pairs of chromosomes, 10 pairs from each of the ancestral species.The information in the sequence sheds light on parts of the plant’s genetic code that control traits like seed size and disease resistance, which are important to plant breeders. But the sequence also revealed more about the origin of peanut during the dawn of agriculture in South America and on the genetic mechanisms that have generated diversity and allowed adaptation to environments around the globe.The mother of peanutUsing the new genome sequence as a framework, the team was able to analyze the variations in more than 200 of the most diverse peanuts from all of over the world. Researchers found characteristic genetic fingerprints shared by all the peanut plants tested, providing new evidence that all modern peanut varieties stem from the same original hybrid.“The new study underlines how peanut’s origin was due to very special circumstances thousands of years ago. Ancient farmers transported one species into the range of another, allowing their hybridization and the formation of a new crop species,” said Soraya Leal-Bertioli, a senior research scientist with the UGA Institute of Plant Breeding, Genetics and Genomics and the CAES Department of Plant Pathology. Scientists with the initiative had previously found the male donor of the original hybrid and origin of peanut’s “B” subgenome. In this new study they identified the female donor, tracking the population of wild ancestral peanut that contributed the peanut “A” subgenome in Rio Seco, Argentina. These individuals form the “mother” population of peanut.But the evidence that all modern peanuts can be traced to a single original hybrid sets up another mystery, Leal-Bertioli said. How does a plant with such a narrow genetic base develop so many variations and varieties?ShufflingMost flowering plant species rely on animals or weather to spread their pollen or seeds to other plants to generate genetic diversity. Pollen and seeds can travel for miles, spreading newly occurring traits to new populations.But peanuts, which produce their seeds underground, don’t do that. It took early human farmers and their long-distance transport of seeds to get the first two ancestral peanut parents together.Since then, however, the plant has used a new mechanism for creating diversity.The peanut has two sets of chromosomes, one from each ancestor. By analyzing more than 200 cultivated peanuts from all over the world, it was shown that different landraces and cultivars have shuffled the genetic material of the ancestors and deleted some sections altogether. Over the past the 10,000 years, this shuffling has happened thousands of times — allowing a much faster-paced generation of diversity than if the plants simply relied on mutation.In a greenhouse on the UGA campus, the Bertiolis have worked with hybrids that recreate the original ancestral peanut and observed the shuffling in real time. They documented its effects in the spontaneous appearance of different flower colors. These same genetic mechanisms generate other types of variation as well, said David Bertioli.The phenomenon explains the tremendous about of diversity seen in peanuts today, said Leal-Bertioli.For this research, the International Peanut Genome Initiative brought together scientists from the U.S., Argentina, China, India, Japan and France. The initial sequencing was carried out at the Hudson Alpha Institute in Huntsville, Alabama, and USDA Agricultural Research Service Genomics and Bioinformatics Research Unit in Stoneville, Mississippi. The project was funded by the National Peanut Board, the American Peanut Shellers Association, and other growers, shellers, manufacturers and allied industries.For more information about how UGA scientists have helped crack the peanut’s genetic code, visit www.youtube.com/watch?v=xDcmm82hIUU.last_img read more

Cargo shipments of Botox and cheese replace passengers for starving airlines

first_imgCoronavirus: Cargo shipments of Botox and cheese replace passengers for starving airlines Search quotes, news & videoslast_img